Anesthesia practice requires constant and precise conversion of units to ensure patient safety. Errors in conversion can lead to significant morbidity and mortality. Here is a comprehensive list of conversion tables and formulas routinely used by anesthesia providers.
1. Weights and Measures (The Foundation)
These are the most fundamental conversions, performed for virtually every patient.
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| Weight | Pounds (lbs) | Kilograms (kg) | Divide by 2.2 | Essential for all drug dosing. All pediatric and most adult drug doses are calculated in mcg/kg or mg/kg. |
| Weight | Kilograms (kg) | Pounds (lbs) | Multiply by 2.2 | Communicating with patients or in settings where lbs are the standard. |
| Height | Inches (in) | Centimeters (cm) | Multiply by 2.54 | Used for pediatric dosing (e.g., Broselow tape), estimating endotracheal tube size, and equipment selection. |
| Temperature | Fahrenheit (°F) | Celsius (°C) | Subtract 32, then multiply by 5/9 | Monitoring core body temperature for hypothermia or malignant hyperthermia. |
| Temperature | Celsius (°C) | Fahrenheit (°F) | Multiply by 9/5, then add 32 | Communicating with patients or staff unfamiliar with Celsius. |
2. Drug Dosing and Concentrations
Critical for preparing and administering medications safely.
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| Drug Mass | Milligrams (mg) | Micrograms (mcg) | Multiply by 1,000 | For potent drugs like fentanyl, epinephrine, and phenylephrine where doses are in the mcg range. |
| Drug Mass | Micrograms (mcg) | Milligrams (mg) | Divide by 1,000 | Reversing the above, e.g., when documenting total dose given. |
| Concentration | Percent (%) | mg/ml | Multiply by 10 | Crucial for drawing up drugs. Propofol 1% = 10 mg/ml. Lidocaine 2% = 20 mg/ml. Phenylephrine 1% = 10 mg/ml. |
| Dose | mg/kg | Total Dose (mg) | Weight (kg) × Dose (mg/kg) | Calculating a one-time dose, such as for an antibiotic or induction agent. |
3. Infusion Rates (Vasoactive Drugs)
This is one of the most frequent and high-stakes calculations in anesthesia, especially in the ICU and for major cases.
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| Infusion Rate | mcg/kg/min | ml/hr | (Dose × Weight × 60) / (Concentration in mcg/ml) | The cornerstone of vasoactive infusion management. See detailed formula below. |
| Dopamine/Dobutamine | mcg/kg/min | ml/hr | (Weight in kg) / (Concentration in mg/ml) | The "Rule of 4s": If you mix 400mg in 250ml (1.6 mg/ml), the ml/hr is roughly the wt in kg. More common is the "Rule of 6s" (600mg in 100ml, 6 mg/ml). |
| Norepinephrine/Epinephrine/Phenylephrine | mcg/min | ml/hr | (Dose × 60) / (Concentration in mcg/ml) | The "Rule of Threes": Mix 3mg in 50ml (60 mcg/ml) or 6mg in 100ml. Then, ml/hr = mcg/min. |
Detailed Formula: mcg/kg/min to ml/hr
This is the universal formula for any weight-based infusion.
Example: A 70 kg patient needs a norepinephrine infusion starting at 0.05 mcg/kg/min. You have a standard mix of 4 mg norepinephrine in 250 ml D5W.
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Identify Variables:
- Dose = 0.05 mcg/kg/min
- Weight = 70 kg
- Concentration = 4 mg in 250 ml
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Unify Units: Convert concentration to mcg/ml.
- 4 mg = 4,000 mcg
- Concentration = 4,000 mcg / 250 ml = 16 mcg/ml
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Apply the Formula:
- Infusion Rate (ml/hr) = (Dose × Weight × 60) / (Concentration)
- Infusion Rate = (0.05 mcg/kg/min × 70 kg × 60 min/hr) / (16 mcg/ml)
- Infusion Rate = (210) / 16 = 13.125 ml/hr
4. Physiological Pressures
Used for interpreting hemodynamic and respiratory monitoring.
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| Airway/CVP Pressure | Centimeters of Water (cmH₂O) | Millimeters of Mercury (mmHg) | Divide by 1.36 | Converting central venous pressure (CVP) or airway pressures to a unit comparable to blood pressure. |
| Airway/CVP Pressure | Millimeters of Mercury (mmHg) | Centimeters of Water (cmH₂O) | Multiply by 1.36 | Standard for airway pressures on ventilators (Peak, Plateau, PEEP). |
| Blood Gas Pressure | Kilopascals (kPa) | Millimeters of Mercury (mmHg) | Multiply by 7.5 | Converting ABG values (PaO₂, PaCO₂) from kPa (used outside the US) to the familiar mmHg. |
| Blood Gas Pressure | Millimeters of Mercury (mmHg) | Kilopascals (kPa) | Divide by 7.5 | Converting ABG values to kPa. |
5. Laboratory Values
Essential for managing metabolic and electrolyte disturbances.
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| Glucose | mg/dl | mmol/L | Divide by 18 | Managing intraoperative and ICU blood glucose. |
| Creatinine | mg/dl | µmol/L | Multiply by 88.4 | Assessing renal function for drug clearance. |
| Hemoglobin | g/dl | g/L | Multiply by 10 | Assessing oxygen-carrying capacity and transfusion triggers. |
| Electrolytes (Na⁺, K⁺, Cl⁻) | mEq/L | mmol/L | Often 1:1 | For monovalent ions, the values are numerically identical. Important for managing electrolyte replacement. |
6. Volatile Anesthetics
Used for calculating and delivering inhalational anesthetics.
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| MAC | Age-adjusted MAC | % on Vaporizer | MAC_age = MAC_40yr × (1 - (Age-40) × 0.01) | Calculating the appropriate MAC for an elderly patient. |
| MAC | Fraction (Fi) | % | Multiply by 100 | Converting the gas monitor display (e.g., 0.015) to a percentage (1.5%). |
Common MAC Values (for a 40-year-old)
- Sevoflurane: 2.0%
- Desflurane: 6.0%
- Isoflurane: 1.2%
Safety and Best Practices
- Double-Check Everything: Always have a colleague verify high-risk drug infusions and calculations, especially for pediatric patients or potent vasoactive drugs.
- Use Smart Pumps: Modern infusion pumps have drug libraries that allow you to enter the dose in mcg/kg/min, and the pump calculates the ml/hr. This dramatically reduces errors but requires you to enter the patient's weight and drug concentration correctly.
- Label Everything: Clearly label all syringes and infusion bags with the drug name, concentration, and time of preparation.
- Know Your "Rules of Thumb": Rules like the "Rule of Threes" for norepinephrine are excellent for quick mental checks to ensure a pump rate is in the correct ballpark. If a rate seems wrong, it probably is. Stop and re-calculate.
