Esmolol

Esmolol Injection

Esmolol is an ultra-short-acting, cardioselective, beta-1 adrenergic receptor antagonist. Its ultra-short duration of action makes it uniquely suited for the dynamic environment of the operating room.

Continue reading

EMLA Cream

EMLA Cream

EMLA stands for Eutectic Mixture of Local Anesthetics. It is a topical anesthetic used to provide temporary, superficial analgesia of intact skin. Its utility lies in its ability to reduce the pain of needle procedures, making it an invaluable tool, especially in pediatrics and for patients with needle phobia.

Continue reading

Entonox

Color-coded Entonox Cylinders

Entonox is a pre-mixed, colorless, non-flammable gas consisting of 50% nitrous oxide (N₂O) and 50% oxygen (O₂). It is a fundamental and widely used analgesic in many clinical settings, from the emergency department to the delivery suite.

Continue reading

Etomidate

Etomidate is a potent, non-barbiturate hypnotic agent used for the induction of general anesthesia. Its primary claim to fame is its remarkable hemodynamic stability, making it a go-to drug for patients with compromised cardiovascular function.

Continue reading

Dantrolene Sodium

Dantrolene in MH Cart

Dantrolene is the definitive, life-saving antidote for Malignant Hyperthermia (MH), a rare but fulminant hypermetabolic crisis triggered by specific anesthetic agents. It is a direct-acting skeletal muscle relaxant that works at the cellular level, not at the neuromuscular junction.

Continue reading

Dexamethasone

Clinical effects of Dexamethasone

Dexamethasone is a long-acting glucocorticoid essential for anesthesiologists. It’s a cornerstone of ERAS protocols, providing potent prophylaxis against PONV, reducing airway and tissue edema, and offering opioid-sparing analgesia. While highly effective, its use requires careful monitoring for perioperative hyperglycemia, especially in diabetic patients.

Continue reading

Dobutamine

Mechanism of Action of Dobutamine

Dobutamine is a potent synthetic inotrope primarily acting on β1-adrenergic receptors to dramatically increase cardiac contractility. Its principal role is in managing acute decompensated heart failure and other low cardiac output states, where the therapeutic goal is to boost the heart’s pumping force without significantly increasing vascular resistance.

Continue reading

Dopamine

Mechanism of Action of Dopamine

Dopamine is a potent endogenous neurotransmitter used clinically as a vasopressor and inotrope, uniquely characterized by its dose-dependent effects on the cardiovascular system. At low doses, it acts on dopaminergic receptors to increase renal blood flow; at intermediate doses, it stimulates β1-receptors to boost cardiac contractility; and at high doses, it activates α1-receptors to cause potent vasoconstriction.

Continue reading

Diclofenac Sodium

For the anesthesiologist, diclofenac is a valuable tool for opioid-sparing, multimodal analgesia. Its use demands a strict risk-benefit analysis, vigilantly balancing its potent anti-inflammatory pain relief against the significant perioperative dangers of bleeding, renal injury, and gastrointestinal complications.

Continue reading

Cisatracurium

Cisatracurium_Structure

Cisatracurium offers predictable paralysis with unique advantages. Its organ-independent metabolism and lack of histamine release make it perfect for hemodynamically unstable patients and those with renal or hepatic failure. Discover why this NMBA is a critical tool in modern anesthesia and critical care.

Continue reading