Malignant Hyperthermia(MH)
Malignant Hyperthermia is a rare, life-threatening, inherited pharmacogenetic disorder of skeletal muscle. It is characterized by a hypermetabolic crisis triggered by exposure to certain volatile anesthetic gases (e.g., sevoflurane, desflurane, isoflurane) and the depolarizing muscle relaxant succinylcholine. In susceptible individuals, these agents induce an uncontrolled release of calcium from the…
