Perioperative Anaphylaxis Grading System

The Perioperative Anaphylaxis Grading System (Ring and Messmer) classifies reactions from Grade I (cutaneous only) to Grade IV (cardiac arrest). It guides management: adrenaline is first‑line for Grades II–IV, with fluids and airway support escalating by grade. Essential for rapid recognition, treatment, and post‑event allergy investigation.

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